The Bad News On Dissociatives... - Olney's Lesions

Well, we were all hoping it wouldnt happen, but the report is finally in on damage to your brain from dissociatives. Olney's lesions are small holes in specific areas of the brain due to extensive use of dissociative drugs like, DXM, PCP, Ketamine, Nitrous Oxide, and others. An overview of this document:

• Dissociatives definitely cause brain damage if used heavily. One sub-anaesthetic "line dose" of ketamine, an equivalent dose of PCP, or a third plateau DXM dose, is probably at least as damaging to your brain as a few day "bender" on hard liquor, and possibly more so because it affects specific areas of the brain.

• The risk of brain damage is worse the longer you stay high at any given time; constant moderate-dose use is probably just as damaging as a brief, high-dose use.

• Reaching the anaesthetic level is exceedingly hard on your brain (4th Plateau).

• Ketamine is probably the least harmful, PCP the most, and DXM somewhere in the middle, but this is a rough guesstimate. Nitrous oxide is brief acting, but it too may be dangerous; it is also known to damage both central and peripheral nerves by depleting vitamin B12.

Read the full report here


Psychosis can happen with drugs such as dissociatives. When a psychadelic drug is taken, many chemical reactions are taking place in your brain. Sometimes on very high doses your brain cannot take anymore of it and just "snaps". After that you may come to your senses in a padded room, hence... *not fun*. This doesnt usually happen unless its a very high dosage, the person uses it regularly, and/or they have had mental problems before.

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