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Default 1-piperidinocyclohexanecarbonitrile (PCC)

1-piperidinocyclohexanecarbonitrile, also known as PCC is a potential contaminant in street PCP when this chemical has been used as an intermediate in synthesis. It was referred to originally as 'Compound 44' and demonstrated an ability to cause total mortality in aphids at concentrations of 0.35 percent, and 60% mortality at concentrations of 0.2 percent. Quite a high toxicity was thus observed for this compound, in addition to many of the other closely related aminonitriles studied. This toxicity would later prove to have devastating consequences for the uninformed street drug PCP user (as well as many clandestine chemists themselves). In addition the combination of PCP and PCC shows additive synergism in regard to toxicity. [1]

1-piperidinocyclohexanecarbonitrile molecule

  1. ^ Davis, W. Marvin, et al. "Lethal synergism of phencyclidine with a precursor and contaminant, 1-piperidinocyclohexanecarbonitrile ." Life Sciences. 26.24 (1980): Volume 26, Issue 24, 16 June 1980, Pages 2105-2111.http://dx.doi.org/10.1016/0024-3205(80)90596-2


Created by viscosity, 07-19-2010 at 06:43 PM
Last edited by viscosity, 07-28-2010 at 07:08 PM
Last comment by viscosity on 07-21-2010 at 08:00 PM
5 Comments, 1,334 Views

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