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Originally Posted by Arm
no medical use.
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Wrong.
Alcohol is considered an antidote For methanol poisoning:
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Specific antidote is ethanol and this should be given IV as a 10% solution in 5% dextrose A loading dose of 0.6g/kg should be given followed by an lVI of 0.07g/kg/hr for non-drinkers (regular drinkers should receive 0. 16g/kg/hr)
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http://www-clinpharm.medschl.cam.ac....n/poison9.html
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PURPOSE: To test nicotine patch treatment for a patient with a defined mutation for autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) whose seizures were refractory to standard antiepileptic therapy.
METHODS: Open and double-blind trials of nicotine patches in an "n-of-one" study. The double-blind trial comprised periods during which either placebo or nicotine patches were each used for three periods of 2 weeks, randomized in a double-blind manner.
RESULTS: In an open study, nicotine patches reduced seizures from 1.65 +/- 2.36 to 0.01 +/- 0.0 seizures per day (p < 0.0001). In a double-blinded placebo-controlled phase, the average frequency of seizures on nicotine versus placebo was 0 +/- 0 versus 0.56 +/- 1.14 seizures per day (p < 0.0001).
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http://www.ncbi.nlm.nih.gov/pubmed/12919397