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drdªv€
04-11-2007, 07:18 PM
Published: Wednesday, April 11, 2007
The phrase “popping pills” has become more frequently used in conversation among college-aged students in recent times. Other terms such as overdose and abuse have also become more integrated into the daily vocabulary.

Addition of these terms to daily speech is one indication, among other information gathered from research and surveys, that reveals the increasing occurrence of prescription and over-the-counter pill misuse.

The abuse of prescription and over-the-counter drugs is on the rise among college students, said Daniel Walter, cofounder of Students for a Sensible Drug Policy, a trend the group is working to curb.

“We are trying to inform students on the risks of using certain drugs recreationally, including those available by prescription and those bought over the counter,” Walter said.

A common misconception that prescription and over-the-counter drugs are safer than illicit drugs is contributing to a staggering increase in their abuse among students as young as 9 years old, according to the California Poison Control System.

The number of overdoses due to dextromethorphan (DXM), a common ingredient in cough suppressants, reported in patients between the ages of 9 and 17 has increased more than tenfold in the last few years, from 23 cases in 1999 to 375 cases in 2004.

“Students need to know exactly what the dangers are when they misuse these drugs,” Walter said.

Nearly half of all over-the-counter drugs – more than 125 products – contain DXM, the cough suppressant that can be found in stores in caplet or liquid form, according to the U.S. Department of Health and Human Services.

When taken in large doses, DXM can produce a high, and, according to the U.S. Department of Health and Human Services, if taken in high doses, can impair judgment and mental functioning, which results in coordination loss, dizziness, hallucinations, brain damage, seizures and possibly death.

Emergency room visits related to abuse of pharmaceuticals increased 21 percent from 2004 to 2005, while visits related to illicit drugs and alcohol remained the same during that period, according to the Drug Abuse Warning Network.

In a Substance Abuse and Mental Health Services Administration report, emergency room visits related to anti-anxiety drugs increased 19 percent and visits related to prescription painkillers went up 24 percent.

But the dangers of abuse are very different between prescription drugs and drugs available over the counter.

According to the National Institute on Drug Abuse, approximately 15 million Americans in 2003 reported using prescription drugs for nonmedical reasons at least once during the year.

Dr. Michele Van Vranken from the Nemours Foundation said prescription drugs are only safe for the individual who actually has the prescription for them since a doctor had examined these people and knows most accurately the drug’s safety relative to the individual.

Commonly misused prescription drugs include painkillers, central nervous system depressants and stimulants, Vranken said.

Prescription painkillers, called opioids, are used to treat pain or relieve coughs and diarrhea by attaching to receptors in the central nervous system and stopping the brain from receiving pain messages.

Depressants such as Nembutal, Valium, and Xanax are used to treat anxiety, tension, and sleep disorders by slowing down brain activity.

Inversely, stimulants such as Ritalin, Adderall, and Strattera increase brain activity to increase alertness, attention and energy.

When used correctly, these can treat narcolepsy, attention deficit hyperactivity disorder (ADHD), depression and obesity.

And like all drug abuse, using prescription drugs for the wrong reasons has usually resulted in serious risks for a person’s health.

Just a single dose of a prescription painkiller can lower a person’s breathing rate and even lead to death.

The risk is higher when these painkillers are taken with other substances such as alcohol, antihistamines and other depressants.


http://www.dailybruin.ucla.edu/news/2007/a...cal_drugs_rise/ (http://www.dailybruin.ucla.edu/news/2007/apr/11/sciencehealth_abuse_pharmaceutical_drugs_rise/)

Psychotic Break
04-11-2007, 07:44 PM
When taken in large doses, DXM can produce a high, and, according to the U.S. Department of Health and Human Services, if taken in high doses, can impair judgment and mental functioning, which results in coordination loss, dizziness, hallucinations, brain damage, seizures and possibly death.

:nono:

janks
04-11-2007, 07:48 PM
Originally posted by Psychotic Break@Apr 11 2007, 06:44 PM
When taken in large doses, DXM can produce a high, and, according to the U.S. Department of Health and Human Services, if taken in high doses, can impair judgment and mental functioning, which results in coordination loss, dizziness, hallucinations, brain damage, seizures and possibly death.

:nono:
i love when reporters do their research B)

Walkaway
04-11-2007, 08:01 PM
DXM is well-documented as being capable of causing both seizures and death, and the question of whether or not it causes (permanent) brain damage is still open (though I suspect that it does not, or only does so in a minority of the heaviest abusers).

Kang
04-11-2007, 08:26 PM
Originally posted by Space Monkey@Apr 11 2007, 04:01 PM
DXM is well-documented as being capable of causing both seizures and death, and the question of whether or not it causes (permanent) brain damage is still open (though I suspect that it does not, or only does so in a minority of the heaviest abusers).
I understand the seizures [vaguely], but wouldn't it take a beyond recreational dose to cause brain damage? [Other than olney's lesions]

Walkaway
04-11-2007, 08:31 PM
I don't really know, and no one else does either.

The overwhelming amount of evidence seems to indicate that recreational doses of DXM are unlikely to cause permanent brain damage unless you're a temporal lobe epileptic*. However, this is not the same as saying that it does not cause brain damage.

*additionally, it is possible that an otherwise healthy individual might sustain brain damage as a result of seizure activity and/or hypoxia (at high doses) and/or currently unknown mechanisms

Kang
04-11-2007, 08:34 PM
I'm so glad I'm not an epileptic.

nastyvicks
04-11-2007, 09:33 PM
Originally posted by Mike+Apr 11 2007, 07:26 PM--></span><table border='0' align='center' width='95%' cellpadding='3' cellspacing='1'><tr><td>QUOTE (Mike @ Apr 11 2007, 07:26 PM)</td></tr><tr><td id='QUOTE'> <!--QuoteBegin--Space Monkey@Apr 11 2007, 04:01 PM
DXM is well-documented as being capable of causing both seizures and death, and the question of whether or not it causes (permanent) brain damage is still open (though I suspect that it does not, or only does so in a minority of the heaviest abusers).
I understand the seizures [vaguely], but wouldn't it take a beyond recreational dose to cause brain damage? [Other than olney's lesions] [/b][/quote]
Respiratory depression could lead to brain damage, but yeah, you would probably have to take an extraordinary dose of dxm to reach that point.

Walkaway
04-11-2007, 09:35 PM
Respiratory depression could lead to brain damage, but yeah, you would probably have to take an extraordinary dose of dxm to reach that point.
See above ("hypoxia").

Eloivore
04-12-2007, 10:08 AM
There is no exact definition of "brain damage".

Everyone (almost everyone?) would consider killing off an abnormally large number of neurons to be brain damage. Same with loss of dendritic or axonal structure that causes a permanent loss of information. On the other hand, (hopefully) nobody considers temporary neurotransmitter depletion, or activation of normal learning mechanisms, to be brain damage.

OK, now, what about driving neurons into states which they could never possibly reach through physiological means, such that they can never return to a physiological state? Pretty much any drug is *theoretically* capable of doing so.